actual lab book

This is going to be an oft-updated lab book entry of my IVF cycle. Very boring. Useful in posterity. Feel free to disregard, esp. when I update it every two days.

March 4, 2015: Cycle day 1

March 5, cd 2: baseline ultrasound. Uterine lining: 3 mm, ovaries: no cysts, follicles too small to see.

March 6-7, cd 3-4: 150 U gonal-f, 75 U Menopur nightly.

March 8, cd 5: E2 = less than 5. Menopur dose increased to 150 U.

March 8-12, cd 5-9: 150 U gonal-f, 150 U Menopur nightly.

March 11, cd 8: E2 = 190. Ultrasound: uterine lining: 5 mm, trilaminar. Ovaries: R: 5 @ 7mm, 2 @ 6mm. L: 2@7mm, 5@6mm, 2@<6mm. All is well, carry on with current protocol.

March 13-15, cd 10-12: 150 U gonal f, 150 U Menopur, 1 syringe Ganirilex nightly.

March 14, cd 11 – E2 = 1220. Ultrasound – Uterine lining missed, I was sleepy. Ovaries: R: 11 follicles between 6-11 mm. L: 12 follicles between 7-11 mm. All is well, a bit slow on purpose, carry on with current protocol.

March 16th, cd 13 – E2 = 1890. Ultrasound – uterine lining 11.1. Ovaries: many many follicles, I lost count because he just rattled them out really fast. Largest was 13 mm, most were in the 10-11 mm range. All is well, but now it’s kinda slow for real. Bump gonal-f up to 200 units per night and come in for daily monitoring.

March 16-18, cd 13-15 – 200 U gonal-f, 150 U Menopur, 1 syringe Ganirilex nightly.

March 17th, cd 14 – E2 = 2889. Ultrasound – uterine lining 9.5 (thinner?! – different Dr. though.). Ovaries: R: 8 (10, 11, 11, 12, 12, 13, 14, 15 mm) and L: 11 (8, 10, 11, 11, 12, 12, 12, 12, 13, 13, 14 mm). All is well, keep on the current dose, predicted trigger is Thursday.

March 18th, cd 15 – E2 = 3847. Ultrasound – uterine lining 9.0 (wha?). Ovaries – many follicles, I decided not to count along and avoid obsessing. Lead follicle is 18 mm. Two at 16 mm. Many around 12-14mm. Because E2 has not gone crazy, safe to stim another day to let the littler guys catch up more. Keep on current dose, come in tomorrow.

March 19th, cd 16 – E2 = 4100. Ultrasound – lining 10 mm. Ovaries – 22 follicles 14 mm +. Lead follicle is 20 mm. Trigger tonight.

March 19th, cd 16 – One syringe ganirilex taken between 5-6 pm, 10,000 U HcG taken at 7:30 pm. No lupron trigger, oddly, I think because my E2 was not crazy high, they are less worried about OHSS?

March 21st, cd 18 – egg retrieval at 7:30 am, 26 eggs retrieved. 25 mature. 19 fertilized (13 to IVF – 8 fertilized. 12 to ICSI – 11 fertilized).

March 24th, cd 21 – transfer of two embryos, one 7-cell, one 9-cell, both graded 3 for fragmentation (1-6, 1 is best). Rest continued to culture out to day 5.

March 26th, cd 23 – one 3bb blastocyst frozen.

Luteal Phase meds:

Medrol. March 21-25th, cd 18-22: one tablet in the morning.

Progesterone in oil (PIO). March 21-?, cd 18-?: 0.5 mL for two days, then 1 mL daily in the evenings until told to stop.

Estrace: March 25th-?, cd 22-?: one tablet twice daily until told to stop.

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