We did a day three transfer today, of two embryos. I got the call confirming the appointment was a go, and my heart sank. Not again, not such terrible quality that we cannot push to day 5, not after all we have tried.
Not so! Dramatic improvement. Though I would much rather even MORE improvement, I cannot say this looks the same, not at all.
My clinic grades embryos by number of cells (even numbers preferred), fragmentation (1-5, 1-2 is preferred), and symmetry (scale seems to be 1-3 where 1 is best).
To push to blast on day 5, they want at least 6 embryos with more than 6 cells (6-8 ideal), and fragmentations scores of 1 or 2. I think symmetry plays into it, but I’m not sure how.
A recap from last time, at this same stage. 19 fertilized embryos. Exactly zero met the criteria. Two were borderline (right cell # (though both odd), fragmentation of 3. We transferred both of those at day 3, BFN). One of the other not-even-borderline ones became our FET blastocyst (CP).
This time: 17 fertilized embryos. 5 meet that criteria (only one is uneven in cell #), and a further 5 are borderline (6-8 cells, all with fragmentation of 3, 2 with odd cell numbers). We transferred two 8 cell embryos – one was an 8-1-1, and one was an 8-2-1. The 8-1-1 had begun to compact, in prep for becoming a morula (next stage in embryogenesis).
Am I happy we did a day 3 transfer? No. The doctor who did the transfer said we were right on the border for pushing to day 5 – if it was our first cycle, he would have said we should push forward but given how poorly our last cycle had worked out, he wanted to be safe and transfer some good healthy ones today. I appreciate that, and will keep my fingers crossed some of the other good-to-moderate embryos continue developing. And also that my uterus can take down its ‘for rent’ sign in two weeks. We’ll see, their credit check hasn’t come through yet.